Journal article
The murine p75 TNF receptor promoter region: DNA sequence and characterization of a cis-acting silencer.
- Abstract:
-
The promoter region of the murine p75 TNF receptor (TNF-R) was isolated from a mouse genomic DNA cosmid library. The promoter region is devoid of TATA box and has the characteristics of a house keeping gene since it contains multiple SP1 binding sites. Its mRNA has different initiation sites in different lymphoid cell lines. This promoter confers transcriptional activity to heterologous reporter genes. Deletion analysis showed that there is a silencer element located upstream from position -8...
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- Publication status:
- Published
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- Publisher copy:
- 10.1016/s0161-5890(99)00022-x
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Bibliographic Details
- Journal:
- Molecular immunology
- Volume:
- 36
- Issue:
- 2
- Pages:
- 125-134
- Publication date:
- 1999-02-01
- DOI:
- EISSN:
-
1872-9142
- ISSN:
-
0161-5890
- Source identifiers:
-
481581
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:481581
- UUID:
-
uuid:c9b22c58-4fc1-44bc-a35a-3c3368dc3621
- Local pid:
- pubs:481581
- Deposit date:
- 2014-08-29
Terms of use
- Copyright date:
- 1999
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