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Chimeric O1K foot-and-mouth disease virus with SAT2 outer capsid as an FMD vaccine candidate

Abstract:

Foot-and-mouth disease virus (FMDV) is highly contagious and infects cloven-hoofed domestic livestock leading to foot-and-mouth disease (FMD). FMD outbreaks have severe economic impact due to production losses and associated control measures. FMDV is found as seven distinct serotypes, but there are numerous subtypes within each serotype, and effective vaccines must match the subtypes circulating in the field. In addition, the O and Southern African Territories (SAT) serotypes, are relatively ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1038/s41598-018-31856-x

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Role:
Author
ORCID:
0000-0002-4480-5439
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Role:
Author
ORCID:
0000-0002-4355-4367
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
MSD Doctoral Training Centre
Role:
Author
ORCID:
0000-0003-1192-5917
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Scientific Reports Journal website
Volume:
8
Issue:
1
Pages:
13654
Publication date:
2018-09-12
Acceptance date:
2018-08-24
DOI:
EISSN:
2045-2322
ISSN:
2045-2322
Pubs id:
pubs:920236
URN:
uri:c98ddef1-6dee-48be-89b8-3a4e114124de
UUID:
uuid:c98ddef1-6dee-48be-89b8-3a4e114124de
Local pid:
pubs:920236
Language:
English
Keywords:

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