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Memory inflation: continuous accumulation of antiviral CD8+ T cells over time.

Abstract:

CD8+ T lymphocytes play an important role in the control of intracellular pathogens during both acute and persistent infections. This is particularly true in the case of persistent herpesviruses such as human CMV, which are typified by large virus-specific CD8+ T cell populations during viral latency. To understand the origin of these populations and the factors shaping them over time, we investigated the CD8+ T cell response after murine CMV (MCMV) infection. The kinetics of the acute respon...

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Publication status:
Published

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Publisher copy:
10.4049/jimmunol.170.4.2022

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Journal:
Journal of Immunology
Volume:
170
Issue:
4
Pages:
2022-2029
Publication date:
2003-02-01
DOI:
EISSN:
1550-6606
ISSN:
0022-1767
Source identifiers:
29571

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