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Antenatal screening in Oxford for fetal neural tube defects.

Abstract:

Between May 1975 and the end of 1977, 6443 antenatal patients were screened mainly between 16 and 22 weeks of pregnancy for neural tube defects (NTDs) at the John Radcliffe Hospital, Oxford, by maternal serum alpha-fetoprotein (AFP) measurement; a take-up of 72 per cent. Seventeen out of 18 (94 per cent) patients with open NTD pregnancies (9 out of 9 with anencephaly and 8 out of 9 with open spina bifida) had positive screening tests, and all except one were offered and accepted a termination...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Nuffield Department of Population Health, Clinical Trial Service Unit
Role:
Author
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Journal:
British journal of obstetrics and gynaecology
Volume:
86
Issue:
2
Pages:
91-100
Publication date:
1979-02-05
DOI:
EISSN:
1471-0528
ISSN:
0306-5456
URN:
uuid:c972a818-491d-406b-970c-6c80baf7d88a
Source identifiers:
79367
Local pid:
pubs:79367

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