Objective Immune activation is associated with morbidity/mortality in HIV-infection despite antiretroviral therapy (ART). We investigated whether microbial translocation drives immune activation in HIV-infected Ugandan children.
Methods Nineteen markers of immune activation/inflammation were measured over 96 weeks in HIV-infected Ugandan children in CHAPAS-3 (ISRCTN69078957) and HIV-uninfected age-matched controls. Microbial translocation was asses... Expand abstract
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- Peer reviewed
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- Oxford University Press Publisher's website
- Journal of Infectious Diseases Journal website
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0022-1899 and 1537-6613
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- Fitzgerald et al.
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- © The Authors 2018. Published by Oxford University Press for the Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Microbial translocation does not drive immune activation in Ugandan children with HIV
National Institute for Health Research More from this funder
University College London More from this funder
United Kingdom Department for International Development More from this funderExpand funders...
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