- Abstract:
-
In the presence of epistasis multilocus association tests of human complex traits can provide powerful methods to detect susceptibility variants. We undertook multilocus analyses in 1924 type 2 diabetes cases and 2938 controls from the Wellcome Trust Case Control Consortium (WTCCC). We performed a two-dimensional genome-wide association (GWA) scan using joint two-locus tests of association including main and epistatic effects in 70,236 markers tagging common variants. We found two-locus assoc...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1111/j.1469-1809.2010.00629.x
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- Journal:
- Annals of human genetics
- Volume:
- 75
- Issue:
- 1
- Pages:
- 10-19
- Publication date:
- 2011-01-05
- DOI:
- EISSN:
-
1469-1809
- ISSN:
-
0003-4800
- URN:
-
uuid:c9663122-f3c8-4615-947e-44ea595db350
- Source identifiers:
-
103646
- Local pid:
- pubs:103646
- Copyright date:
- 2011
Journal article
Genome-wide association scan allowing for epistasis in type 2 diabetes.
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