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Immunology of disorders of neuromuscular transmission.

Abstract:

The neuromuscular junction (NMJ) is a prototype synapse and myasthenia gravis is the prototypic antibody-mediated disorder. There are now three other disorders of neuromuscular transmission caused by antibodies to other essential components of the NMJ. Antibodies to the muscle-specific kinase, MuSK, are defining a new form of myasthenia that can be associated with muscle atrophy. Antibodies to voltage-gated calcium channels are responsible for muscle weakness and autonomic dysfunction in the ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
Acta neurologica Scandinavica. Supplementum
Volume:
183
Issue:
s183
Pages:
1-7
Publication date:
2006-01-01
DOI:
EISSN:
1600-5449
ISSN:
0065-1427
URN:
uuid:c963a7dd-f8b4-45b6-8d8b-fca5846a8eb9
Source identifiers:
241049
Local pid:
pubs:241049

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