Journal article
Bromodomain protein 4 discriminates tissue-specific super-enhancers containing disease-specific susceptibility loci in prostate and breast cancer.
- Abstract:
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Background
Epigenetic information can be used to identify clinically relevant genomic variants single nucleotide polymorphisms (SNPs) of functional importance in cancer development. Super-enhancers are cell-specific DNA elements, acting to determine tissue or cell identity and driving tumor progression. Although previous approaches have been tried to explain risk associated with SNPs in regulatory DNA elements, so far epigenetic readers such as bromodomain containing protein 4 (B...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.2MB)
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- Publisher copy:
- 10.1186/s12864-017-3620-y
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Authors
Contributors
+ Wrightson, R
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Nuffield Department of Population Health; Cancer Epidemiology Unit
Oxford college:
Wolfson College
Role:
Contributor
Funding
Department of Health
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Canadian Institute for Health Research
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Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- BMC Genomics Journal website
- Volume:
- 18
- Issue:
- 1
- Pages:
- 270
- Publication date:
- 2017-03-01
- Acceptance date:
- 2017-03-11
- DOI:
- EISSN:
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1471-2164
- ISSN:
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1471-2164
- Pmid:
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28359301
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:689058
- UUID:
-
uuid:c962f18f-77c7-48ea-886c-3782a5dba900
- Local pid:
- pubs:689058
- Deposit date:
- 2018-01-08
Terms of use
- Copyright holder:
- Mills et al
- Copyright date:
- 2017
- Notes:
- © The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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