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Transmission dynamics of hyper-endemic multi-drug resistant Klebsiella pneumoniae in a Southeast Asian neonatal unit: A longitudinal study with whole genome sequencing

Abstract:

Background

Klebsiella pneumoniae is an important and increasing cause of life-threatening disease in hospitalized neonates. Third generation cephalosporin resistance (3GC-R) is frequently a marker of multi-drug resistance, and can complicate management of infections. 3GC-R K. pneumoniae is hyper-endemic in many developing country settings, but its epidemiology is poorly understood and prospective studies of endemic transmission are lacking. We aimed to determine the transmission ...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.3389/fmicb.2018.01197

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; NDM Experimental Medicine
van Kleef, E More by this author
Oonsivilai, M More by this author
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Grant:
Grant Number Example
National Institute for Health Research More from this funder
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Microbiology Journal website
Volume:
9
Issue:
JUN
Pages:
1197
Publication date:
2018-06-05
Acceptance date:
2018-05-16
DOI:
ISSN:
1664-302X
Pubs id:
pubs:857828
URN:
uri:c952e810-c1b2-4653-9ba3-72cdb9ec55d1
UUID:
uuid:c952e810-c1b2-4653-9ba3-72cdb9ec55d1
Local pid:
pubs:857828

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