Journal article
NAADP receptors
- Abstract:
-
Of the established Ca2+-mobilizing messengers, NAADP is arguably the most tantalizing. It is the most potent, often efficacious at low nanomolar concentrations, and its receptors undergo dramatic desensitization. Recent studies have identified a new class of calcium-release channel, the two-pore channels (TPCs), as the likely targets for NAADP regulation, even though the effect may be indirect. These channels localized at endolysosomes, where they mediate local Ca2+ release, and have highligh...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1101/cshperspect.a035071
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Authors
Funding
Bibliographic Details
- Publisher:
- Cold Spring Harbor Laboratory Press Publisher's website
- Journal:
- Cold Spring Harbor Perspectives in Biology Journal website
- Volume:
- 11
- Issue:
- 11
- Article number:
- a035071
- Publication date:
- 2019-06-10
- Acceptance date:
- 2019-04-02
- DOI:
- EISSN:
-
1943-0264
- Pmid:
-
31182546
- Source identifiers:
-
1013660
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:1013660
- UUID:
-
uuid:c948d652-8cf9-429c-a11e-775e3f0997b3
- Local pid:
- pubs:1013660
- Deposit date:
- 2019-06-27
Terms of use
- Copyright holder:
- Cold Spring Harbor Laboratory Press
- Copyright date:
- 2019
- Rights statement:
- © 2019 Cold Spring Harbor Laboratory Press; all rights reserved.
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