Journal article icon

Journal article

Role of the neuropilin ligands VEGF164 and SEMA3A in neuronal and vascular patterning in the mouse.

Abstract:

Blood vessels and neurons use similar guidance cues to control their behaviour during embryogenesis. The semaphorin SEMA3A was originally identified as a repulsive cue for developing axons that acts by signalling through receptor complexes containing NRP1 and A-type plexins. SEMA3A also competes with the VEGF164 isoform of vascular endothelial growth factor for binding to NRP1 to modulate the migration of endothelial cells in vitro. Surprisingly, we have found that SEMA3A and semaphorin signa...

Expand abstract

Actions


Access Document


Publisher copy:
10.1002/9780470319413.ch18

Authors


Vieira, JM More by this author
Schwarz, Q More by this author
Ruhrberg, C More by this author
Journal:
Novartis Foundation symposium
Volume:
283
Pages:
230-235
Publication date:
2007
DOI:
EISSN:
1935-4657
ISSN:
1528-2511
URN:
uuid:c91cac51-0245-441f-a40f-65abac71f416
Source identifiers:
428937
Local pid:
pubs:428937

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP