Journal article
Stereotypic wheel running decreases cortical activity in mice
- Abstract:
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Prolonged wakefulness is thought to gradually increase 'sleep need' and influence subsequent sleep duration and intensity, but the role of specific waking behaviours remains unclear. Here we report the effect of voluntary wheel running during wakefulness on neuronal activity in the motor and somatosensory cortex in mice. We find that stereotypic wheel running is associated with a substantial reduction in firing rates among a large subpopulation of cortical neurons, especially at high speeds. ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(pdf, 1.6MB)
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- Publisher copy:
- 10.1038/ncomms13138
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Authors
Funding
+ Biotechnology and Biological Sciences Research Council
More from this funder
Grant:
Industrial CASE grant (BB/K011847/1
Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Nature Communications Journal website
- Volume:
- 7
- Article number:
- 13138
- Publication date:
- 2016-10-17
- DOI:
- ISSN:
-
2041-1723
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:653426
- UUID:
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uuid:c91421f5-a6bb-4b30-9e14-5dd72398ab03
- Local pid:
- pubs:653426
- Deposit date:
- 2016-11-09
Terms of use
- Copyright holder:
- Fisher et al
- Copyright date:
- 2016
- Notes:
- This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
- Licence:
- CC Attribution (CC BY)
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