- Abstract:
-
Prolonged wakefulness is thought to gradually increase 'sleep need' and influence subsequent sleep duration and intensity, but the role of specific waking behaviours remains unclear. Here we report the effect of voluntary wheel running during wakefulness on neuronal activity in the motor and somatosensory cortex in mice. We find that stereotypic wheel running is associated with a substantial reduction in firing rates among a large subpopulation of cortical neurons, especially at high speeds. ...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 1.6MB)
-
- Publisher copy:
- 10.1038/ncomms13138
-
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- Grant:
- Industrial CASE grant (BB/K011847/1)
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Nature Communications Journal website
- Volume:
- 7
- Pages:
- Article: 13138
- Publication date:
- 2016-10-17
- DOI:
- ISSN:
-
2041-1723
- Pubs id:
-
pubs:653426
- URN:
-
uri:c91421f5-a6bb-4b30-9e14-5dd72398ab03
- UUID:
-
uuid:c91421f5-a6bb-4b30-9e14-5dd72398ab03
- Local pid:
- pubs:653426
- Language:
- English
- Keywords:
- Copyright holder:
- Fisher et al.
- Copyright date:
- 2016
- Notes:
- This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
Journal article
Stereotypic wheel running decreases cortical activity in mice
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