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Dopamine dependency of oscillations between subthalamic nucleus and pallidum in Parkinson's disease.

Abstract:

The extent of synchronization within and between the nuclei of the basal ganglia is unknown in Parkinson's disease. The question is an important one because synchronization will increase postsynaptic efficacy at subsequent projection targets. We simultaneously recorded local potentials (LPs) from the globus pallidus interna (GPi) and subthalamic nucleus (STN) in four awake patients after neurosurgery for Parkinson's disease. Nuclei from both sides were recorded in two patients so that a total...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience, Biomedical Research Centre
Oliviero, A More by this author
Mazzone, P More by this author
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Journal:
The Journal of neuroscience : the official journal of the Society for Neuroscience
Volume:
21
Issue:
3
Pages:
1033-1038
Publication date:
2001-02-05
EISSN:
1529-2401
ISSN:
0270-6474
URN:
uuid:c909eb5f-7faa-4bd9-88b0-13149d7bd6e9
Source identifiers:
368940
Local pid:
pubs:368940

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