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Analysis of gamma delta V region usage in normal and diseased human intestinal biopsies and peripheral blood by polymerase chain reaction (PCR) and flow cytometry.

Abstract:

The intestinal population of gamma delta T cell receptor (TCR)-bearing cells was characterized with regard to V delta and V gamma subtype expression. For this purpose, we utilized V gene-specific PCR of mRNA prepared from intestinal biopsies. Predominant expression of the V delta 1 subtype was demonstrated in the small intestine of patients with coeliac disease and in the inflamed colon of patients with inflammatory bowel diseases (IBD: ulcerative colitis and Crohn's disease) as well as in co...

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Publication status:
Published

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Journal:
Clinical and experimental immunology More from this journal
Volume:
99
Issue:
1
Pages:
57-64
Publication date:
1995-01-01
DOI:
EISSN:
1365-2249
ISSN:
0009-9104
Language:
English
Keywords:
Pubs id:
pubs:476000
UUID:
uuid:c9003e86-3d6d-4dc4-8923-e289bded707e
Local pid:
pubs:476000
Source identifiers:
476000
Deposit date:
2014-07-17

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