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Effects of intermittent lower limb ischaemia on coronary blood flow and coronary resistance in pigs.

Abstract:

AIM: Intermittent limb ischaemia prior to cardiac ischaemia is a cardioprotective stimulus. This study was to investigate whether this peripheral stimulus had any effects on basal coronary blood flow and resistance, and to explore its potential mechanisms by studying the effect of femoral nerve transection and Katp blockade by glibenclamide. METHODS: Remote ischaemic preconditioning (rIPC) was induced by four 5-min cycles of lower limb ischaemia. Coronary resistance was measured using standar...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
Journal:
Acta physiologica (Oxford, England)
Volume:
190
Issue:
2
Pages:
103-109
Publication date:
2007-06-01
DOI:
EISSN:
1748-1716
ISSN:
1748-1708
Source identifiers:
105198
Language:
English
Keywords:
Pubs id:
pubs:105198
UUID:
uuid:c8f52e64-38b7-463f-b94b-26d571ca5477
Local pid:
pubs:105198
Deposit date:
2012-12-19

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