Journal article
The frequency and mechanism of loss of heterozygosity on chromosome 11q in breast cancer.
- Abstract:
-
Loss of heterozygosity (LOH, allele loss) occurs frequently on the long arm of chromosome 11 in breast cancer. Seventy-one paired tumour/normal DNA samples from breast cancer patients under 50 years old were studied for allele loss at four microsatellite loci on 11q: D11S29 (11q23.3), NCAM (11q22-q23), D11S968 (11qtel), and D11S1313 (11qcen). The maximum frequency of LOH (approximately 35 per cent) was found at the D11S29 and NCAM loci. This result is consistent with previous studies and the ...
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- Publisher copy:
- 10.1002/(sici)1096-9896(199609)180:1<38::aid-path638>3.0.co;2-c
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Bibliographic Details
- Journal:
- Journal of pathology
- Volume:
- 180
- Issue:
- 1
- Pages:
- 38-43
- Publication date:
- 1996-09-01
- DOI:
- EISSN:
-
1096-9896
- ISSN:
-
0022-3417
- Source identifiers:
-
72312
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:72312
- UUID:
-
uuid:c8f488fd-cf8f-4e19-baab-7ed8e8b0cd6e
- Local pid:
- pubs:72312
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1996
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