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Journal article

New oral anticoagulants in atrial fibrillation and acute coronary syndromes: ESC Working Group on Thrombosis-Task Force on Anticoagulants in Heart Disease position paper.

Abstract:

Until recently, vitamin K antagonists were the only available oral anticoagulants, but with numerous limitations that prompted the introduction of new oral anticoagulants targeting the single coagulation enzymes thrombin (dabigatran) or factor Xa (apixaban, rivaroxaban, and edoxaban) and given in fixed doses without coagulation monitoring. Here we review the pharmacology and the results of clinical trials with these new agents in stroke prevention in atrial fibrillation and secondary preventi...

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Publication status:
Published

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Publisher copy:
10.1016/j.jacc.2012.02.008

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Journal:
Journal of the American College of Cardiology
Volume:
59
Issue:
16
Pages:
1413-1425
Publication date:
2012-04-01
DOI:
EISSN:
1558-3597
ISSN:
0735-1097
Source identifiers:
325165
Language:
English
Keywords:
Pubs id:
pubs:325165
UUID:
uuid:c8eb0376-ab62-42e7-9108-d43cf5826aff
Local pid:
pubs:325165
Deposit date:
2012-12-19

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