Rapid elimination by glomerular filtration of free prostate specific antigen and human kallikrein 2 after renal transplantation.

Journal article

PURPOSE: The low molecular mass and short half-life of free (f) prostate specific antigen (PSA) implies elimination from blood by glomerular filtration. In addition, patients with terminal renal failure have increased fPSA in serum but there have been sparse data reported on the rates and pathways of elimination of PSA complexes and human kallikrein 2 (hK2). We studied glomerular filtration dependent elimination of fPSA and hK2 in patients with renal insufficiency undergoing successful renal...

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Authors: Bruun, L; Ekberg, H; Bjørk, T; Lilja, H; Høglund, P

• Journal: Journal of urology
• Volume: 171
• Issue: 4
• Pages: 1432-1435
• Publication date: 2004-04-01
• DOI: 10.1097/01.ju.0000118580.19344.68
• EISSN: 1527-3792
• ISSN: 0022-5347
• Language: English
• Keywords: Prostate-Specific Antigen; Kidney Transplantation; Male; Tissue Kallikreins; Humans; Female; Middle Aged; Time Factors; Glomerular Filtration Rate; Aged