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Development of enzyme-linked immunosorbent assay for human leptospirosis serodiagnosis using leptospira secretome antigen

Abstract:

Secretome (extracellular proteins) has been considered as a potential diagnostic biomarker, vaccine and therapeutic candidates for bacterial infections. In this research, secretomes of two reference Leptospira spp, namely, pathogenic L. interrogans serovar Autumnalis strain Akiyami and saprophytic L. biflexa serogroup Semaranga serovar Patoc strain P136 were evaluated for their immunogenicity to microscopic agglutination test (MAT)-positive leptospirosis patients’ sera in IgM- and IgG-ELISA...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


Maneewatchararangsri, S More by this author
Reamtong, O More by this author
Kalambaheti, T More by this author
Pumirat, P More by this author
Vanaporn, M More by this author
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Faculty of Tropical Medicine, Mahidol University More from this funder
Publisher:
Seameo Regional Tropical Medicine and Public Health Publisher's website
Journal:
Southeast Asian Journal of Tropical Medicine and Public Health Journal website
Volume:
48
Issue:
3
Pages:
576-584
Publication date:
2017
ISSN:
0125-1562
Pubs id:
pubs:824991
URN:
uri:c894df35-fdf4-423a-b0fc-558a24973736
UUID:
uuid:c894df35-fdf4-423a-b0fc-558a24973736
Local pid:
pubs:824991

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