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Severe dengue categories as research endpoints—results from a prospective observational study in hospitalised dengue patients

Abstract:

Severe dengue was perceived as one clinical disease entity until the WHO 2009 classification stratified it into severe vascular leakage, severe bleeding, and severe organ dysfunction. The objectives of this study were to investigate the potential use of severe dengue categories as endpoints for intervention research. 271 patients with severe dengue among 1734 confirmed dengue patients were followed prospectively in this hospital-based observational study in Latin America and Asia. We compared...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0003-3459-3812
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Role:
Author
ORCID:
0000-0002-6707-7876
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Role:
Author
ORCID:
0000-0002-7452-4208
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Role:
Author
ORCID:
0000-0002-4703-0798
Publisher:
Public Library of Science
Journal:
PLoS Neglected Tropical Diseases More from this journal
Volume:
14
Issue:
3
Article number:
e0008076
Place of publication:
United States
Publication date:
2020-03-04
Acceptance date:
2020-01-19
DOI:
EISSN:
1935-2735
ISSN:
1935-2727
Pmid:
32130212
Language:
English
Keywords:
Pubs id:
1093884
Local pid:
pubs:1093884
Deposit date:
2020-06-19

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