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The role of immunity in mosquito-induced attenuation of malaria virulence.

Abstract:

A recent study found that mosquito-transmitted (MT) lines of rodent malaria parasites elicit a more effective immune response than non-transmitted lines maintained by serial blood passage (non-MT), thereby causing lower parasite densities in the blood and less pathology to the host. The authors attribute these changes to higher diversity in expression of antigen-encoding genes in MT cf. non-MT lines. Alternative explanations that are equally parsimonious with these new data, and results from ...

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Publication status:
Published

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Publisher copy:
10.1186/1475-2875-13-25

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Journal:
Malaria journal More from this journal
Volume:
13
Issue:
1
Pages:
25
Publication date:
2014-01-01
DOI:
EISSN:
1475-2875
ISSN:
1475-2875
Language:
English
Keywords:
Pubs id:
pubs:447864
UUID:
uuid:c88e684c-30da-4c62-bfec-13c7080fec6a
Local pid:
pubs:447864
Source identifiers:
447864
Deposit date:
2014-02-14

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