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Thesis

The role of CD5 in T lymphocyte activation

Abstract:

In order to prevent autoimmune diseases the immune system must be tightly regulated. One mechanism that the immune system uses to prevent autoimmunity is through the use of regulatory receptors on the surface of T lymphocytes. In this thesis I have concentrated on the role of one such receptor, CD5, in T lymphocyte activation. CD5 is a member of the scavenger receptor cysteine rich superfamily and is expressed, along with the closely related CD6, on T cells and a subset of B cells. CD5...

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Institution:
University of Oxford
Research group:
Neil Barclay
Oxford college:
Linacre College
Department:
Medical Sciences Division

Contributors

Role:
Supervisor
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Funding agency for:
Erica Lacey
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:c88d2845-4454-4b98-9814-64b9bbf22e04
Local pid:
ora:12165

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