- Abstract:
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Background: Hypoxia may contribute to the pathogenesis of various diseases of the vascular wall. Hypoxia-inducible factors (HIFs) are nuclear transcriptional factors that regulate the transcription of genes that mediate cellular and tissue homeostatic responses to altered oxygenation. This article reviews the published literature on and discusses the role of the HIF pathway in diseases involving the vascular wall, including atherosclerosis, arterial aneurysms, pulmonary hypertension, vascular...
Expand abstract - Publisher copy:
- 10.1016/j.jvs.2013.02.240
-
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- Journal:
- Journal of Vascular Surgery
- Volume:
- 58
- Issue:
- 1
- Pages:
- 219-230
- Publication date:
- 2013-07-05
- DOI:
- EISSN:
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1097-6809
- ISSN:
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0741-5214
- URN:
-
uuid:c8895106-61e8-4904-9eb3-fb0b8abb0c98
- Source identifiers:
-
411509
- Local pid:
- pubs:411509
- Language:
- English
- Copyright date:
- 2013
Journal article
Hypoxia-inducible factor pathway and diseases of the vascular wall
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