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Cellular landmarks of Trypanosoma brucei and Leishmania mexicana

Abstract:

The kinetoplastids Trypanosoma brucei and Leishmania mexicana are eukaryotes with a highly structured cellular organisation that is reproduced with great fidelity in each generation. The pattern of signal from a fluorescently tagged protein can define the specific structure/organelle that this protein localises to, and can be extremely informative in phenotype analysis in experimental perturbations, life cycle tracking, post-genomic assays and functional analysis of organelles. Using the vast...

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Publication status:
Published
Peer review status:
Peer reviewed

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
More from this funder
Name:
Wellcome Trust
Grant:
211075/Z/18/Z
Publisher:
Elsevier
Journal:
Molecular and Biochemical Parasitology More from this journal
Volume:
230
Pages:
24-36
Publication date:
2018-12-11
Acceptance date:
2018-12-10
DOI:
EISSN:
1872-9428
ISSN:
0166-6851
Pmid:
30550896
Language:
English
Pubs id:
pubs:953029
UUID:
uuid:c8799d78-e3b2-45e1-9ef3-5ea480c8c230
Local pid:
pubs:953029
Deposit date:
2019-01-19

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