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Journal article

Statistical parametric mapping of (99m)Tc-HMPAO-SPECT images for the diagnosis of Alzheimer's disease: normalizing to cerebellar tracer uptake.

Abstract:

BACKGROUND: For a quantitative comparison of images obtained during (99m)Tc-hexamethylpropylene amine oxime (HMPAO) single-photon emission computed tomography (SPECT), brain activity values are usually normalized to a reference region. In studies of Alzheimer-type dementia (ATD), the cerebellum is often used as a reference region, assuming that it is spared any major pathological involvement. Statistical parametric mapping (SPM) may enhance the evaluation of SPECT scans in ATD patients. Howe...

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Publication status:
Published

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Publisher copy:
10.1006/nimg.2002.1259

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Institution:
University of Oxford
Department:
Oxford, MSD, Psychiatry
Role:
Author
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Journal:
NeuroImage
Volume:
17
Issue:
3
Pages:
1193-1202
Publication date:
2002-11-05
DOI:
EISSN:
1095-9572
ISSN:
1053-8119
URN:
uuid:c8788ae7-f836-4e22-b60f-e2811869ac62
Source identifiers:
139177
Local pid:
pubs:139177

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