The complement system is an essential component of the innate and acquired immune system, and consists of a series of proteolytic cascades that are initiated by the presence of microorganisms. In health, activation of complement is precisely controlled through membrane-bound and soluble plasma-regulatory proteins including complement factor H (fH; ref. 2), a 155 kDa protein composed of 20 domains (termed complement control protein repeats). Many pathogens have evolved the ability to avoid imm...Expand abstract
- Publication status:
- Publisher copy:
- Copyright date:
Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates.
Views and Downloads
If you are the owner of this record, you can report an update to it here: Report update to this record