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Journal article

Pro-opiocortin related peptides in human pituitary and ectopic ACTH secreting tumours.

Abstract:

Basal and stimulated secretion of N-terminal pro-opiocortin (Pro-gamma-MSH), ACTH and LPH from seven pituitary and three ectopic ACTH secreting tumours have been studied in vitro using a perfused isolated cell system. The peptides were shown to be released concomitantly and in equimolar amounts. The pituitary tumours responded to stimulation with rat stalk median eminence extracts (SME) and synthetic AVP. However, peptide release from the ectopic tumours, although pulsatile, remained autonomo...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, OCDEM
Role:
Author
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Journal:
Clinical endocrinology
Volume:
18
Issue:
3
Pages:
211-218
Publication date:
1983-03-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:c86b6349-beae-461d-be43-45b1439dd1c4
Source identifiers:
138755
Local pid:
pubs:138755

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