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A theoretical framework for transitioning from patient-level to population-scale epidemiological dynamics: influenza A as a case study

Abstract:

Predictions with within-host models and/or infection data collected in longitudinal cohort studies. However, most multi-scale models are complex and require significant modelling expertise to run. We formulate an alternative multi-scale modelling framework using a compartmental model with multiple infected stages. In the large-compartment limit, our easy-to-use framework generates identical results compared to previous more complicated approaches. We apply our framework to the case study of ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1098/rsif.2020.0230

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Sub department:
Mathematical Institute
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Sub department:
Mathematical Institute
Role:
Author
ORCID:
0000-0002-0146-9164
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Sub department:
Mathematical Institute
Role:
Author
Publisher:
Royal Society, The Publisher's website
Journal:
Interface Journal website
Volume:
17
Issue:
166
Article number:
20200230
Publication date:
2020-05-13
Acceptance date:
2020-04-06
DOI:
EISSN:
1742-5662
ISSN:
1742-5689
Language:
English
Keywords:
Pubs id:
1099036
Local pid:
pubs:1099036
Deposit date:
2020-04-08

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