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The PTPN22 R263Q polymorphism is a risk factor for rheumatoid arthritis in caucasian case-control samples.

Abstract:

OBJECTIVE: Recently a functional PTPN22 variant (R263Q rs33996649) was associated with systemic lupus erythematosus (SLE). The aim of this paper was to analyze the influence of this polymorphism on the risk of RA METHODS: 5,579 RA patients were recruited from outpatient clinics from 6 different countries: Spain, New Zealand, UK, Norway, The Netherlands and Germany. 5,392 healthy controls (HC) were recruited from the same areas. There was 100% power to detect an effect equivalent to that obser...

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Publication status:
Published

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Publisher copy:
10.1002/art.30145

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Journal:
Arthritis Rheum
Volume:
63
Issue:
2
Pages:
365-372
Publication date:
2010-11-15
DOI:
EISSN:
1529-0131
ISSN:
0004-3591
URN:
uuid:c858898d-5b1e-483c-a8d4-e41843a78924
Source identifiers:
108833
Local pid:
pubs:108833
Language:
English

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