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Efficacy of artemisinin-based and quinine-based treatments for uncomplicated falciparum malaria in pregnancy: a protocol for systematic review and individual patient data (IPD) meta-analysis

Abstract:

Introduction: Pregnant women are more vulnerable to malaria leading to adverse impact on both mothers and fetuses. However, knowledge on the efficacy and safety of antimalarials in pregnancy is limited by the paucity of randomised control trials and the lack of standardised protocols in this special subpopulation. Pooling individual patient data (IPD) for meta-analysis could address in part these limitations to summarise accurately the currently available evidence on treatment e...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1136/bmjopen-2018-027503

Authors


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Role:
Author
ORCID:
0000-0002-1667-9287
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0002-3011-4952
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
ORCID:
0000-0003-1621-3257
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Publisher:
BMJ Publishing Group Publisher's website
Journal:
BMJ Open Journal website
Volume:
9
Issue:
8
Article number:
e027503
Publication date:
2019-08-22
Acceptance date:
2019-07-23
DOI:
ISSN:
2044-6055
Pmid:
31444179
Source identifiers:
1048776
Language:
English
Keywords:
Pubs id:
pubs:1048776
UUID:
uuid:c8556c50-59eb-4011-9377-2dbd7571f306
Local pid:
pubs:1048776
Deposit date:
2019-09-06

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