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Journal article

Recognition of CG inversions in DNA triple helices by methylated 3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one nucleoside analogues.

Abstract:
Substituted 3H-pyrrolo[2,3-d]pyrimidin-2(7H)-one nucleoside analogues have been synthesised from 5-alkynyl-uridine derivatives, incorporated into triplex forming oligonucleotides (TFOs) and found to selectively bind CG inversions with enhanced affinity compared to T.
Publication status:
Published

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Publisher copy:
10.1039/b502325d

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Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Journal:
Chemical communications (Cambridge, England)
Issue:
20
Pages:
2555-2557
Publication date:
2005-05-05
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
URN:
uuid:c84cb328-2211-4f32-bb54-df40964b1dd3
Source identifiers:
400044
Local pid:
pubs:400044

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