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Congenital toxoplasmosis: continued parasite proliferation in the fetal brain despite maternal immunological control in other tissues.

Abstract:

BACKGROUND: Congenital toxoplasmosis is a serious condition but little is known of the natural history of parasite development and associated fetal tissue destruction. METHODS: Two cases identified by ultrasound underwent induced abortion at 21 and 30 weeks' gestation. At autopsy, the placenta and fetal organs were examined by histology and immunocytochemistry employing anti-Toxoplasma stage-specific antibodies to confirm diagnosis and also provide information on the stage of parasite develo...

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Publication status:
Published

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Publisher copy:
10.1093/cid/cis882
Journal:
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America More from this journal
Volume:
56
Issue:
2
Pages:
204-208
Publication date:
2013-01-01
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
Language:
English
Keywords:
Pubs id:
pubs:356291
UUID:
uuid:c82d622c-4d41-4808-8658-bb93a88b3995
Local pid:
pubs:356291
Source identifiers:
356291
Deposit date:
2013-11-16

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