Journal article
An analytical method for disentangling the roles of adhesion and crowding for random walk models on a crowded lattice
- Abstract:
- Migration of cells and molecules in vivo is affected by interactions with obstacles. These interactions can include crowding effects, as well as adhesion/repulsion between the motile cell/molecule and the obstacles. Here we present an analytical framework that can be used to separately quantify the roles of crowding and adhesion/repulsion using a lattice-based random walk model. Our method leads to an exact calculation of the long time Fickian diffusivity, and avoids the need for computationally expensive stochastic simulations.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Access Document
- Files:
-
-
(Accepted manuscript, pdf, 124.8KB)
-
- Publisher copy:
- 10.1088/1478-3975/13/5/05LT02
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Authors
Funding
Bibliographic Details
- Publisher:
- Institute of Physics Publisher's website
- Journal:
- Physical Biology Journal website
- Volume:
- 13
- Issue:
- 5
- Publication date:
- 2016-09-01
- Acceptance date:
- 2016-08-24
- DOI:
- EISSN:
-
1478-3975
- ISSN:
-
1478-3967
- Source identifiers:
-
661051
Item Description
- Keywords:
- Pubs id:
-
pubs:661051
- UUID:
-
uuid:c81cb8f8-20d2-4df4-8b06-e39ec205e9fd
- Local pid:
- pubs:661051
- Deposit date:
- 2016-12-01
Terms of use
- Copyright holder:
- IOP Publishing Ltd
- Copyright date:
- 2016
- Notes:
- © 2016 IOP Publishing Ltd
If you are the owner of this record, you can report an update to it here: Report update to this record