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Journal article

CAMPATH-IH in multiple sclerosis.

Abstract:

In a pilot study, seven patients with multiple sclerosis were treated with CAMPATH-IH which targets the CD52 antigen present on lymphocytes and monocytes. There was a substantial reduction in disease activity as measured by gadoliunium-enhancing lesions on MRI. Encouraged by this result a further seven patients have been treated with CAMPATH-IH; four also received anti-CD4 antibody. Lymphopaenia developed rapidly and was sustained for at least one year. In 12 patients, the first infusion of a...

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Journal:
Multiple sclerosis (Houndmills, Basingstoke, England) More from this journal
Volume:
1
Issue:
6
Pages:
357-365
Publication date:
1996-07-01
EISSN:
1477-0970
ISSN:
1352-4585
Language:
English
Keywords:
Pubs id:
pubs:9825
UUID:
uuid:c80ed68c-f326-4d76-8974-ead343bae2a6
Local pid:
pubs:9825
Source identifiers:
9825
Deposit date:
2012-12-19

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