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Early lesions following aerosol infection of rhesus macaques (Macaca mulatta) with Mycobacterium tuberculosis strain H37RV.

Abstract:

As part of a study to investigate early changes following exposure to aerosols of Mycobacterium tuberculosis (Mtb), 10 rhesus macaques (Macaca mulatta) were infected with high (731 colony forming units [cfu]), medium (70 cfu) or low (7 cfu) doses of Mtb, and tissues were examined at 2 and 3 weeks post infection (wpi). Clinical disease was not observed. Results of advanced imaging and pathological findings were compared with respect to the delivered dose and time post infection. Magnetic reson...

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Publication status:
Published

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Publisher copy:
10.1016/j.jcpa.2013.05.005

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Journal:
Journal of comparative pathology
Volume:
149
Issue:
4
Pages:
475-485
Publication date:
2013-11-05
DOI:
EISSN:
1532-3129
ISSN:
0021-9975
URN:
uuid:c80995f8-5879-4ae1-bc70-180fcb73f52d
Source identifiers:
415421
Local pid:
pubs:415421

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