Journal article
Recombinant polymorphic membrane protein D in combination with a novel, second-generation lipid adjuvant protects against intra-vaginal Chlamydia trachomatis infection in mice.
- Abstract:
-
The development of a chlamydial vaccine that elicits protective mucosal immunity is of paramount importance in combatting the global spread of sexually transmitted Chlamydia trachomatis (Ct) infections. While the identification and prioritization of chlamydial antigens is a crucial prerequisite for efficacious vaccine design, it is likely that novel adjuvant development and selection will also play a pivotal role in the translational potential of preclinical Ct vaccines. Although the molecula...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
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- Files:
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(pdf, 1.2MB)
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- Publisher copy:
- 10.1016/j.vaccine.2016.06.081
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Authors
Funding
Bill and Melinda Gates Foundation
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Vaccine Journal website
- Volume:
- 34
- Issue:
- 35
- Pages:
- 4123-4131
- Publication date:
- 2016-07-04
- Acceptance date:
- 2016-06-29
- DOI:
- EISSN:
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1873-2518
- ISSN:
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0264-410X
- Pubs id:
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pubs:718079
- URN:
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uri:c7fd328c-4006-4b3e-87a4-9c2d3e889df5
- UUID:
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uuid:c7fd328c-4006-4b3e-87a4-9c2d3e889df5
- Local pid:
- pubs:718079
Item Description
- Language:
- English
- Keywords:
Terms of use
- Copyright holder:
- Crown Copyright
- Copyright date:
- 2016
- Notes:
- Crown Copyright © 2016 Published by Elsevier Ltd. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
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