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Journal article

Metabolic imaging of acute and chronic infarction in the perfused rat heart using hyperpolarised [1-13C]pyruvate.

Abstract:

Hyperpolarised (13)C MRI can be used to generate metabolic images of the heart in vivo. However, there have been no similar studies performed in the isolated perfused heart. Therefore, the aim of this study was to develop a method for the creation of (13)C metabolite maps of the perfused rat heart and to demonstrate the technique in a study of acute and chronic myocardial infarction. Male Wistar rat hearts were isolated, perfused and imaged before and after occlusion of the left anterior desc...

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Publication status:
Published

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Publisher copy:
10.1002/nbm.2972

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Journal:
NMR in biomedicine
Volume:
26
Issue:
11
Pages:
1441-1450
Publication date:
2013-11-05
DOI:
EISSN:
1099-1492
ISSN:
0952-3480
URN:
uuid:c7f7ccf8-4d54-4d0f-9b48-25c1759dda97
Source identifiers:
407774
Local pid:
pubs:407774

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