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Journal article

The effects of APOE on brain activity do not simply reflect the risk of Alzheimer's disease.

Abstract:

Possession of the APOE-ε4 allele is the best established genetic risk factor for sporadic Alzheimer's disease (AD), while the ε2 allele may confer protection against the disease. Previous functional magnetic resonance imaging (fMRI) studies have shown an effect of APOE genotype on brain function, typically by comparing only ε4 carriers with noncarriers. Here we included a wide range of genotype groups to determine how closely the effects of APOE on brain function are related to differences in...

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Publication status:
Published

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Journal:
Neurobiology of aging More from this journal
Volume:
33
Issue:
3
Pages:
618.e1-618.e13
Publication date:
2012-03-01
DOI:
EISSN:
1558-1497
ISSN:
0197-4580
Language:
English
Keywords:
Pubs id:
pubs:112523
UUID:
uuid:c7f7c499-1e24-4590-a115-128a0b3067b8
Local pid:
pubs:112523
Source identifiers:
112523
Deposit date:
2012-12-19

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