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Lethal malaria: Marchiafava and Bignami were right.

Abstract:
One hundred and twenty years ago, the Italian malariologists Marchiafava and Bignami proposed that the fundamental pathological process underlying lethal falciparum malaria was microvascular obstruction. Since then, several alternative hypotheses have been proposed. These formed the basis for adjunctive interventions, which have either been ineffective or harmful. Recent evidence strongly suggests that Marchiafava and Bignami were right.
Publication status:
Published

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Publisher copy:
10.1093/infdis/jit116

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Turner, GD More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Thailand/Laos MOP
Journal:
The Journal of infectious diseases
Volume:
208
Issue:
2
Pages:
192-198
Publication date:
2013-07-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:c7f29f21-377e-445e-b872-c63d882825a7
Source identifiers:
395912
Local pid:
pubs:395912

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