Nuclear expression of E-cadherin in solid pseudopapillary tumors of the pancreas.

Journal article

CONTEXT: Solid pseudopapillary tumors of the pancreas are rare and have recently been shown to harbor mutations of the beta-catenin gene with resultant nuclear localization of beta-catenin protein to the nucleus. Moreover, there is a close relationship between beta-catenin and E-cadherin. OBJECTIVE: To explore the protein expression of E-cadherin in a series of solid pseudopapillary tumors of the pancreas. PARTICIPANTS: Eighteen cases of solid pseudopapillary tumors of the pancreas. DESIGN: ...

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Authors: Serra, S; Salahshor, S; Fagih, M; Niakosari, F; Radhi, J

• Journal: JOP : Journal of the pancreas
• Volume: 8
• Issue: 3
• Pages: 296-303
• Publication date: 2007-01-01
• EISSN: 1590-8577
• Language: English
• Keywords: Humans; Immunohistochemistry; Cell Nucleus; Adult; Child; Male; Carcinoma, Papillary; Adolescent; Pancreatic Neoplasms; beta Catenin; Cadherins; Neprilysin; Middle Aged; Female; Antigens, CD56