Journal article icon

Journal article

Immunoglobulin heavy chain locus of the rat: striking homology to mouse antibody genes.

Abstract:

DNA encoding the rat diversity segment (D), joining segment (JH), and constant (C) region mu, gamma 2a, gamma 1, gamma 2b, epsilon and alpha of the Ig heavy chain has been isolated from a cosmid library. Restriction mapping allowed us to identify two gene clusters: D-JH-C mu and C gamma 1-C gamma 2b-C epsilon-C alpha in addition to a single C gamma 2a gene. Analysis of genomic DNA by Southern blotting permitted identification of the C gamma 2c gene and led to the proposal of the following gen...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1073/pnas.83.16.6075

Authors


Brüggemann, M More by this author
Diamond, A More by this author
Cobbold, S More by this author
Expand authors...
Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
83
Issue:
16
Pages:
6075-6079
Publication date:
1986-08-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:c7c6642e-9854-40ad-9503-c6c30e892bde
Source identifiers:
25914
Local pid:
pubs:25914

Terms of use


Metrics



If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP