Thesis icon

Thesis

Characterising the role of microglia in the early stages of brain metastasis

Abstract:

Brain metastasis is a common complication of breast cancer patients with poor survival. Histological analysis of autopsy samples from patients with brain metastases suggests that microglia, rather than lymphocytes, are the major immune population activated around the metastatic foci. Microglia and macrophages are versatile immune cells with the ability to polarise to different functional phenotypes depending on the microenvironment they reside in. Clinical and preclinical data report both ...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Division:
MSD
Department:
oncology
Role:
Author

Contributors

Department:
oncology
Role:
Supervisor
More from this funder
Name:
Cancer Research UK
Funding agency for:
Andreou, K
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
UUID:
uuid:c7ba7a7a-8144-48e3-9484-7dedbd90a983
Deposit date:
2017-09-20

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP