Journal article
An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia
- Abstract:
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BACKGROUND:
Expand abstract
The artemisinin-based combination treatment (ACT) of dihydroartemisinin (DHA) and piperaquine (PQP) is a promising novel anti-malarial drug effective against multi-drug resistant falciparum malaria. The aim of this study was to show non-inferiority of DHA/PQP vs. artesunate-mefloquine (AS+MQ) in Asia.
METHODS AND FINDINGS:
This was an open-label, randomised, non-inferiority, 63-day follow-up study conducted in Thailand, Laos and India. Patients aged 3 months to 65 ...
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 343.8KB)
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- Publisher copy:
- 10.1371/journal.pone.0011880
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Authors
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS one Journal website
- Volume:
- 5
- Issue:
- 7
- Pages:
- e11880
- Publication date:
- 2010-07-30
- Acceptance date:
- 2010-05-26
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
- Pmid:
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20689583
- Source identifiers:
-
67531
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:67531
- UUID:
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uuid:c7b079a6-0569-4254-9230-b38e0210d6e4
- Local pid:
- pubs:67531
- Deposit date:
- 2017-04-13
Terms of use
- Copyright holder:
- Valecha et al
- Copyright date:
- 2010
- Notes:
- © 2010 Valecha et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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