Journal article icon

Journal article

An open-label, randomised study of dihydroartemisinin-piperaquine versus artesunate-mefloquine for falciparum malaria in Asia

Abstract:

BACKGROUND:
The artemisinin-based combination treatment (ACT) of dihydroartemisinin (DHA) and piperaquine (PQP) is a promising novel anti-malarial drug effective against multi-drug resistant falciparum malaria. The aim of this study was to show non-inferiority of DHA/PQP vs. artesunate-mefloquine (AS+MQ) in Asia.
METHODS AND FINDINGS:
This was an open-label, randomised, non-inferiority, 63-day follow-up study conducted in Thailand, Laos and India. Patients aged 3 months to 65 ...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1371/journal.pone.0011880

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Expand authors...
Publisher:
Public Library of Science Publisher's website
Journal:
PloS one Journal website
Volume:
5
Issue:
7
Pages:
e11880
Publication date:
2010-07-30
Acceptance date:
2010-05-26
DOI:
EISSN:
1932-6203
ISSN:
1932-6203
Pmid:
20689583
Source identifiers:
67531
Language:
English
Keywords:
Pubs id:
pubs:67531
UUID:
uuid:c7b079a6-0569-4254-9230-b38e0210d6e4
Local pid:
pubs:67531
Deposit date:
2017-04-13

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP