The role of biologic therapies in the management of systemic vasculitis.

Journal article

The recent development of biologic therapies capable of selectively targeting components of the immune system has revolutionised the treatment of inflammatory arthritides. The steady increase in use of biologic agents coupled with the expansion in the knowledge of the pathogenesis of vascular inflammation has led to their application in the treatment of primary systemic vasculitis. These agents may have a role in addition to or in place of conventional immunosuppression and also be effective ...

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Authors: Chan, A; Flossmann, O; Mukhtyar, C; Jayne, DR; Luqmani, R

• Publication status: Published
• Journal: Autoimmunity reviews
• Volume: 5
• Issue: 4
• Pages: 273-278
• Publication date: 2006-04-01
• DOI: 10.1016/j.autrev.2006.01.003
• EISSN: 1873-0183
• ISSN: 1568-9972
• Language: English
• Keywords: Antibodies, Monoclonal; Cytokines; Humans; Antibodies, Antineutrophil Cytoplasmic; Vasculitis