Membrane-containing viruses with icosahedrally symmetric capsids.

Journal article

Viruses with an icosahedrally symmetric protein capsid and a membrane infect hosts from all three domains of life. Similar architectural principles are shared by different viral families, as exemplified by double-stranded DNA viruses such as PRD1 and STIV. During virus assembly, the membrane lipids are selectively acquired from the host cell. The X-ray structure of bacteriophage PRD1 revealed that the lipids are asymmetrically distributed between the two leaflets and facet length is controlle...

Expand abstract

Authors: Huiskonen, J; Butcher, S

• Publication status: Published
• Journal: Current opinion in structural biology
• Volume: 17
• Issue: 2
• Pages: 229-236
• Publication date: 2007-04-01
• DOI: 10.1016/j.sbi.2007.03.005
• EISSN: 1879-033X
• ISSN: 0959-440X
• Language: English
• Keywords: Humans; Hepatitis B virus; Models, Molecular; Animals; Macromolecular Substances; RNA Phages; Capsid; Alphavirus; Viruses; Flavivirus; Membrane Fusion; Imaging, Three-Dimensional; Herpesviridae