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Adult linear IgA disease and chronic bullous disease of childhood: the association with human lymphocyte antigens Cw7, B8, DR3 and tumour necrosis factor influences disease expression.

Abstract:

Linear IgA disease and chronic bullous disease of childhood are both subepidermal autoimmune blistering diseases. Class I and II major histocompatibility locus (MHC) antigen typing was performed on 60 patients (26 chronic bullous disease of childhood, 34 adult linear IgA disease), and the findings were correlated with the clinical course. The typing was performed using a lymphocyte microcytotoxicity assay, and the results were compared with a reference population of U.K. organ donors. Analysi...

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Publication status:
Published

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Journal:
British journal of dermatology More from this journal
Volume:
141
Issue:
5
Pages:
867-875
Publication date:
1999-11-01
DOI:
EISSN:
1365-2133
ISSN:
0007-0963

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