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Deep brain stimulation of the subthalamic nucleus does not affect the decrease of decision threshold during the choice process when there is no conflict, time pressure or reward

Abstract:

During a decision process the evidence supporting alternative options is integrated over time, and the choice is made when the accumulated evidence for one of the options reaches a decision threshold. Humans and animals have an ability to control the decision threshold, i.e. the amount of evidence that needs to be gathered to commit to a choice, and it has been proposed that the subthalamic nucleus (STN) is important for this control. Recent behavioural and neurophysiological data suggest tha...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1162/jocn_a_01252

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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Publisher:
Massachusetts Institute of Technology Publisher's website
Journal:
Journal of Cognitive Neuroscience Journal website
Volume:
30
Issue:
6
Pages:
876-884
Publication date:
2018-02-28
Acceptance date:
2018-02-03
DOI:
EISSN:
1530-8898
ISSN:
0898-929X
Source identifiers:
823136
Keywords:
Pubs id:
pubs:823136
UUID:
uuid:c79fd475-3ec0-4d8b-8306-73f1b7129150
Local pid:
pubs:823136
Deposit date:
2018-02-08

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