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Journal article

Estimation of the sequestered parasite load in severe malaria patients using both host and parasite markers.

Abstract:

The virulence of the malaria parasite Plasmodium falciparum is due, in part, to its ability to cytoadhere in deep vascular beds. Our inability to quantify the load of sequestered parasites hampers our understanding of the pathophysiological mechanisms involved in disease progression and complicates diagnosis. In this study we evaluate potential biochemical markers of sequestered load by comparing them with estimates of the sequestered load from a statistical model fitted to longitudinal patte...

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Publication status:
Published

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Publisher copy:
10.1017/s0031182005008085

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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Journal:
Parasitology
Volume:
131
Issue:
Pt 4
Pages:
449-458
Publication date:
2005-10-01
DOI:
EISSN:
1469-8161
ISSN:
0031-1820
Source identifiers:
39629

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