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Long-term safety assessment of live attenuated tetravalent dengue vaccines: deliberations from a WHO technical consultation.

Abstract:

Dengue is a rapidly growing public health threat with approximately 2.5 billion people estimated to be at risk. Several vaccine candidates are at various stages of pre-clinical and clinical development. Thus far, live dengue vaccine candidates have been administered to several thousands of volunteers and were well-tolerated, with minimal short-term safety effects reported in Phase I and Phase II clinical trials. Based on the natural history of dengue, a theoretical possibility of an increased...

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Authors


Bentsi-Enchill, AD More by this author
Schmitz, J More by this author
Edelman, R More by this author
Roehrig, JT More by this author
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Journal:
Vaccine
Volume:
31
Issue:
23
Pages:
2603-2609
Publication date:
2013-05-05
DOI:
EISSN:
1873-2518
ISSN:
0264-410X
URN:
uuid:c78a3fbb-0454-4d39-9bb7-686e09361aba
Source identifiers:
405839
Local pid:
pubs:405839

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