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Rheumatoid arthritis: Pathogenic mechanisms and therapeutic targets

Abstract:

Numerous novel therapies are in development for rheumatoid arthritis as a consequence of tremendous progress in understanding pathogenic mechanisms and defining relevant disease cells and molecules. Anti-tumour necrosis factor alpha (TNFα) therapies have been particularly successful and set a new standard for symptom control and attenuation of structural damage to joints. Other potential therapeutic targets across a variety of disease pathways have yet to be fully validated. These include pro...

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Publisher copy:
10.1016/j.ddmec.2004.10.006

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Drug Discovery Today: Disease Mechanisms More from this journal
Volume:
1
Issue:
3
Pages:
289-295
Publication date:
2004-12-01
DOI:
ISSN:
1740-6765
Language:
English
Pubs id:
pubs:225710
UUID:
uuid:c7888c2c-f280-42e8-bc69-98f4022150e9
Local pid:
pubs:225710
Source identifiers:
225710
Deposit date:
2012-12-19

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